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2025-02-14
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Articles
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Lipid Composition Features in Elderly Patients with Ischemic Heart Disease and Chronic Kidney Disease
Мirkhayotov M.M
Tashkent Pediatric Medical Institute
Daminov B.T.
Tashkent Pediatric Medical Institute
##semicolon## ischemic heart disease (IHD)##common.commaListSeparator## chronic kidney disease (CKD)##common.commaListSeparator## blood lipids
सार
As chronic kidney disease (CKD) progresses and the glomerular filtration rate (GFR) declines, lipid metabolism parameters deteriorate: levels of low-density lipoproteins (LDL), triglycerides, and the atherogenic index increase, while high-density lipoprotein (HDL) levels decrease. These changes emphasize the need for lipid profile monitoring in CKD patients, as dyslipidemia is a significant risk factor for cardiovascular complications. CKD treatment should include the correction of lipid metabolism disorders, particularly in patients with low GFR, to reduce the risk of atherosclerotic complications.
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1 Ronco C, McCullough P, Anker S. et al. Cardio-renal syndromes: report from the consensus conference of the Acute Dialysis Quality Initiative. Eur Heart J 2010; 31:703-711.
2 Matsushita K, van der Velde M, Astor BC et al, Chronic Kidney Disease Prognosis Consortium. Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis. Lancet 2010;375(9731):2073-81.
3 Whaley-Connell AT, Vassalotti JA, Collins AJ et al. National Kidney Foundation’s Kidney Early Evaluation Program (KEEP) Annual Data Report 2011: Executive Summary. Am J Kidney Dis. 2012;59(3)(suppl 2):S1-S4.
4 Bakris GL, Serafidis PA, Weir MR et al. ACCOMPLISH Trial Investigators. Renal outcomes with different fixed-dose combination therapies in patients with hypertension at high risk for cardiovascular events (ACCOMPLISH): a prespecified secondary analysis of randomised controlled trial. Lancet 2010;375: 1173-1181.
